Response in mice to erythropoiesis regulatory factors     

J P Lewis  C S Wright  R R Moores  W A Neal  E T Welch  L L Smith  E Gardner  W G Lewis 《American journal of veterinary research》1973,34(10):1367-1368

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Neutral models for the analysis of broad-scale landscape pattern   总被引：47，自引：19，他引：28  

Robert H. Gardner  Bruce T. Milne  Monica G. Turnei  Robert V. O'Neill 《Landscape Ecology》1987,1(1):19-28

The relationship between a landscape process and observed patterns can be rigorously tested only if the expected pattern in the absence of the process is known. We used methods derived from percolation theory to construct neutral landscape models,i.e., models lacking effects due to topography, contagion, disturbance history, and related ecological processes. This paper analyzes the patterns generated by these models, and compares the results with observed landscape patterns. The analysis shows that number, size, and shape of patches changes as a function of p, the fraction of the landscape occupied by the habitat type of interest, and m, the linear dimension of the map. The adaptation of percolation theory to finite scales provides a baseline for statistical comparison with landscape data. When USGS land use data (LUDA) maps are compared to random maps produced by percolation models, significant differences in the number, size distribution, and the area/perimeter (fractal dimension) indices of patches were found. These results make it possible to define the appropriate scales at which disturbance and landscape processes interact to affect landscape patterns.  相似文献   

Haematological and biochemical findings in bovine post-parturient haemoglobinuria and the accompanying Heinz-body anaemia.     

D E Gardner  D Martinovich  D A Woodhouse 《New Zealand veterinary journal》1976,24(6):117-122

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Evidence that Frescon-induced contractures in Lymnaea stagnalis muscles do not depend on intracellular calcium stores: A comparison with caffeine action     

B.L. Brezden  D.R. Gardner 《Pesticide biochemistry and physiology》1983,20(3):278-285

The action of the molluscicide Frescon, which induces contractures in smooth and cross-striated muscles of the freshwater snail Lymnaea stagnalis, was compared with the action of caffeine. The results indicate that the latter agent promotes contractions in Lymnaea muscles by releasing Ca²⁺ from intracellular stores. Such a release could not be attributed to the action of Frescon. Furthermore, the molluscicide did not appear to alter muscle function at the level of the contractile apparatus as it did not affect the time course of caffeine-induced contractions. These results favor the hypothesis that Frescon increases sarcolemmal Ca²⁺ permeability.  相似文献   

Serum gamma glutamyl transferase activity in horses with right or left dorsal displacements of the large colon     

Gardner RB  Nydam DV  Mohammed HO  Ducharme NG  Divers TJ 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2005,19(5):761-764

The purpose of this study was to test the hypothesis that horses with right dorsal displacement of the large colon (RDDLC) have elevations in serum gamma glutamyl transferase (GGT) activity when compared with horses with left dorsal displacement of the large colon (LDDLC). Medical records from 37 horses with RDDLC and 48 horses with LDDLC were reviewed. Horses were included for study if the RDDLC or LDDLC was confirmed by exploratory laparotomy or postmortem examination and if a serum GGT measurement was obtained within 24 hours before surgery. The proportion of horses with GGT activity within or above the reference range was determined. Of 37 horses, 18 (49%; exact binomial 95% confidence interval, 32-66%) with RDDLC and, of 48 horses, 1 (2%; 95% CI, 0-11%) with LDDLC had GGT above the reference range. Horses with RDDLC had higher serum GGT than did horses with LDDLC. Of 37 horses, 36 (97%) with RDDLC were discharged with a good prognosis and none returned as a result of hepatic disease. Evaluation of surgical and postmortem examinations revealed that positioning of the colon in horses with RDDLC results in compression of the bile duct, which can cause extrahepatic bile duct obstruction and a subsequent elevation in serum GGT activity.  相似文献   

FIELD AND EXPERBMENTAL INVESTIGATION OF "WALK-ABOUT" DISEASE OF HORSES (KIMBERLEY HORSE DISEASE) IN NORTHERN AUSTRALIA: OROTALARIA POISONING IN HORSES. PART I.     

A. L. Bose  B.V.Se.  C. A. Gardner  †  J. D. McConnell  B.V.Sc. L. B. Bull  C.B.B  D.V.Sc  F.A.A‡ 《Australian veterinary journal》1957,33(2):25-33

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Goats as a source of serum erythropoietin     

J P Lewis  W A Neal  E T Welch  R R Moores  E Gardner  D A Alford  C S Wright  J D McWhirter 《American journal of veterinary research》1970,31(5):887-889

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Cumulative racing-speed exercise distance cluster as a risk factor for fatal musculoskeletal injury in Thoroughbred racehorses in California     

Leah Estberg  Ian A. Gardner  Susan M. Stover  Bill J. Johnson  James T. Case  Alex Ardans 《Preventive veterinary medicine》1995,24(4):253-263

Thoroughbred racehorses which suffered a fatal musculoskeletal injury (FMI) while racing or race training at a California racetrack during 9 months of 1991 were studied to determine the importance of intensive, high-speed exercise schedules prior to injury. Seventy-seven horses which sustained an FMI while racing and 45 horses which sustained an FMI while race training were successfully matched by race or timed workout session with one control horse and included in the analyses. Race and timed workout (racing-speed exercise) histories were obtained for the case and control horses. Two-month cumulative, racing-speed cutoff distances were calculated from the control horse sample by two methods. Median racing-speed exercise frequencies and distances of the control horses were used to estimate age-specific (2, 3, 4 and ≥ 5 years), 2-month cumulative, racing-speed distances (Method 1). For the second method, the last race or timed workout for each control horse occurring just prior to, or on the date of injury for the matched case horse was identified. Cumulative racing-speed distances 2 months prior to these exercise events were determined for each control horse and used to estimate median age-specific (2, 3, 4 and ≥ 5 years), 2-month cumulative racing-speed distances (Method 2). The cumulative cutoff distances estimated from both methods were used to classify each matched pair according to the presence or absence of a 2-month cumulative, racing-speed distance which exceeded the age-appropriate cutoff distance (exercise distance cluster) within 6 months prior to injury. Manlel-Haenszel matched-pair odds ratios and 95% confidence limits were calculated separately for the racing and race-training fatal injuries. The relative risk for racing FMI was significantly greater for those horses which ran 2-month, cumulative racing and timed workout distances in excess of the cutoff values determined with Method 1 (relative risk (RR) = 3.0, 95% confidence interval (CI) = 1.2, 7.6) and Method 2 (RR = 7.2, 95% CI = 2.6, 20.6). The relative risk for race-training FMI was significantly greater for those horses which ran 2-month, cumulative racing and timed workout distances in excess of the cutoff values determined with Method 2 (RR = 3.4, 95% CI =1.0, 13.2).  相似文献   

Manual of Standards for Diagnostic Tests and Vaccines : International Committee of the OIE (Edited), Office International Des Epizooties, Paris, 1992, 783 pp., softback, ISBN 92-9044-314-6     

I. Gardner 《Preventive veterinary medicine》1994,19(3-4):295-296

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Functional deficiency of polymorphonuclear leukocytes in simian acquired immunodeficiency syndrome     

A T Cheung  M B Gardner 《American journal of veterinary research》1991,52(9):1523-1526

The functional characteristics of polymorphonuclear leukocytes (PMN), considered to be the first line of host defense against infections, from rhesus macaques confirmed to have simian retrovirus (SRV)-induced simian acquired immunodeficiency syndrome (SAIDS), were evaluated. The PMN from SRV antibody-positive macaques without clinical signs were chemotactically responsive. Their phagocytic and killing capabilities were normal, and their cell membranes were highly deformable. However, PMN from SRV antibody-positive macaques and with persistent lymphadenopathy, as well as having at least 3 of the 11 common clinical signs of AIDS, were chemotactically nonresponsive. Their phagocytic and killing capabilities were compromised, and their cell membranes were rigid and nondeformable. In general, PMN from macaques with clinically confirmed SAIDS were functionally deficient. The results are similar to those obtained in other retroviral infections and can be clinically significant, because the host defense deficiency may be responsible for the recurrent and opportunistic infections in SAIDS.  相似文献